A next-generation supplement for comprehensive skin regeneration

Lamelle Pharmaceuticals is redefining the skincare supplement category with the launch of Matricoll ECM: a premium, science-driven, oral anti-ageing supplement engineered to repair, rebuild and protect the skin from within.

Leveraging advanced bioactive peptide technology, Matricoll ECM offers a multi-targeted approach to extracellular matrix (ECM) regeneration.

Skin ageing is characterised by the progressive breakdown of the ECM, the structural network composed primarily of collagen, elastin and hyaluronic acid. While typical oral supplements rely mainly on hydrolysed collagen, these larger peptides are often poorly absorbed, with only an estimated 10%–30% reaching systemic circulation. This limited bioavailability often translates into incomplete or delayed skin benefits.

Matricoll ECM® overcomes these limitations through a sophisticated combination of highly bioavailable peptides and synergistic actives. This multi-layered, ECM-focused strategy supports accelerated skin repair, reduces inflammation, combats oxidative stress and reinforces the skin barrier. Clinical evaluations demonstrate improvements in hydration, elasticity, wrinkle depth and overall radiance, with superior absorption and potency compared to conventional collagen supplements.

Designed for efficiency and ease of use, the formulation offers convenient dosing while providing results comparable to procedural interventions, without downtime, invasiveness or recovery. Its advanced bioactive peptides are engineered for direct absorption and remain effective even in the presence of gut microbiome imbalance – ensuring consistent, predictable outcomes.

What can you expect to see on your skin?

  • Noticeably smoother, firmer, more resilient skin with improved elasticity and bounce.
  • Rebuilt skin structure promoting regeneration and delayed ageing.
  • A healthier, more youthful complexion protected from environmental damage.
  • Revitalised, hydrated, radiant skin due to improved cellular activity and metabolism.
  • Enhanced results from existing skincare and professional treatments through deeper skin receptivity.

“Ingestible beauty has historically focused on collagen in isolation, but ageing is a whole-ECM phenomenon. Matricoll ECM shifts the paradigm by delivering co-ordinated biological signals that stimulate collagen, elastin and hyaluronic acid production simultaneously,” says Dr Bradley Wagemaker, medical director and product formulator at Lamelle Pharmaceuticals.

“For the first time, we can offer a supplement that mirrors the sophistication of in-clinic interventions, giving patients a scientifically validated way to rebuild skin from its foundational matrix outward.”

Matricoll ECM® is now available through select skincare professionals, Lamelle Pharma Shop, aesthetic clinics and authorised retailers.

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